BACKGROUND: Effective and measurable participant recruitment methods are urgently needed for clinical studies in Alzheimer’s disease. OBJECTIVES: To develop methods for measuring recruitment tactics and evaluating effectiveness. METHODS: Recruitment tactics for the Alzheimer’s Disease Neuroimaging Initiative (ADNI3) were measured using… Continue Reading →

The most common dementia worldwide, Alzheimer’s disease is often diagnosed via biomarkers in cerebrospinal fluid, including reduced levels of Aβ1–42, and increases in total tau and phosphorylated tau-181. Here we describe results of a Phase 2a study of a promising… Continue Reading →

With the relentless aging of the population worldwide, two major concerns need our immediate attention: the expected dramatic increase in disease and disability burden, and the decrease in the ratio of working individuals vs. retirees. A comprehensive approach involving experts… Continue Reading →