Aging in humans is highly heterogeneous and its variability increases with increasing age (1). As a consequence, chronological age is of limited utility for diagnosis, prognostication and treatment guidance. In addition, age by itself is of limited use for the… Continue Reading →

The global population of 65-older-people is increasing. These elderly people are mostly living with chronic diseases. The challenge is to improve or preserve the health and quality of life of these people. Current research is focused on identifying individuals who… Continue Reading →

For clinical studies of sarcopenia and frailty, clinically meaningful outcome measures are needed to monitor disease progression, evaluate efficacy of interventions, and plan clinical trials. Physical performance measures including measures of gait speed and other aspects of mobility and strength… Continue Reading →