Due to differences in the definition of frailty, many different screening instruments have been developed. However, the predictive validity of these instruments among community-dwelling older people remains uncertain. Objective: To investigate whether combined (i.e. sequential or parallel) use of available… Continue Reading →

Objectives: Frailty is a pre-disability condition in older persons providing a challenge to Health-Care Systems. Systematic reviews highlight the absence of a gold-standard for its identification. However, an approach based on initial screening by the General Practitioner (GP) seems particularly… Continue Reading →

Aging in humans is highly heterogeneous and its variability increases with increasing age (1). As a consequence, chronological age is of limited utility for diagnosis, prognostication and treatment guidance. In addition, age by itself is of limited use for the… Continue Reading →